Chapter 151: Cowpox
Chapter 151 Cowpox
Xu Liu stood outside the shed and waited anxiously. In fact, he had a vague premonition in his heart that what Lao Ding had was smallpox, but Xu Liu still held out hope, what if it was just ordinary chickenpox?
When Sun Jing came out of the shed, Xu Liu rushed to greet him and asked: "Madam, what disease does Old Ding have?"
Sun Jing said seriously: "It should be smallpox!"
Smallpox represented a terminal disease in the Ming Dynasty, and there were many examples of entire villages dying. When Xu Liu heard that it was smallpox, he was so frightened that he sat down on the ground and cried: "Oh my god, what can I do?"
Lao Xu Ke just had a son!"
Sun Jing ignored the crying Xu Liu, first took the alcohol gauze from Zhao Jing's hand, and wiped his hands and face carefully. Sun Jing himself had antibodies and was not afraid of the smallpox virus, but Zhao Jing and these students did not, so Sun Jing couldn't help it.
careless.
After everything was cleaned up, Sun Jing asked Xu Liu: "Where is Lao Ding from? When did he come to work in your workshop? Who have you come into contact with in the past few days? Where do you sleep at night? Xu Liu, you have to answer in detail!"
Xu Liu wiped away his tears and began to recall everything about Lao Ding. Lao Ding was a worker from a refugee camp. He had been on the island for several months and had been going to and from get off work normally without any problems. A few days ago, Lao Ding took turns to take a break, and Xu Liu gave him He was given a day off and asked to go shopping in Fucheng. After Lao Ding came back, he bought some candies and shared them with his co-workers. At that time, Xu Liu laughed at Lao Ding for spending money randomly.
Sun Jing heard the key information and asked: "When did he come back? Who did he come back to contact?"
Xu Liu thought for a while and said: "I came back three days ago. Lao Ding happened to be on his shift when he came back. He has been looking at the boiler in the workshop these days. He didn't go out except for eating and sleeping. The only people he came into contact with were in the boiler room.
Twelve people!"
Sun Jing breathed a sigh of relief after hearing this. This old man probably contracted the smallpox virus outside. Fortunately, he did not wander around when he returned to the island. Now he only needs to isolate his twelve co-workers!
Sun Jing has experienced the COVID-19 epidemic in later generations and knows very well how to deal with infectious diseases. There are three conditions for the spread of infectious diseases: source of infection, route of transmission, and susceptible persons! As long as these three conditions are grasped, we can
Infectious diseases are controlled within a fixed range.
Without further ado, Sun Jing immediately arranged for the isolation of the twelve people. They were not allowed to enter within fifty meters of the isolation location. At the same time, the boiler workshop was shut down for disinfection. At the same time, all of Lao Ding's belongings, including the tableware he had come into contact with, were removed.
All clothes and bedding were destroyed.
The boiler workshop that Xu Liu was responsible for was mainly responsible for the power of the brick-making machine. If the boiler stopped, the six brick kilns would basically stop production. Xu Liu did not dare to make this decision on his own. He asked: "Madam, if the boiler is stopped, the production must be stopped."
Director Shen approves!”
Director Shen? Sun Jing didn't know how to create Director Shen. She frowned and said, "Go and call Director Shen over quickly. I'll lead these students here to mark the isolation zone!"
After Xu Liu left, Sun Jing led the students to draw isolation zones and isolation points outside the shed. At this time, Xu Liu came back with a young man in his twenties. This young man was Zhao Zhikuan's first apprentice and hired
The brick-burning apprentices Shen Fu and Zhao Zhikuan who came here were handed over to Shen Fu after the brick factory was successfully put into operation. In addition to being responsible for the daily supply of buildings on the island, the brick factory also sold the extra red bricks produced in exchange for money.
Because the brick factory has basically realized mechanization, the red bricks produced are cheap and beautiful, and are very popular in Fucheng. Except for some large households who build houses because of
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Except for the traditional blue bricks, most of the other brick and tile markets are occupied by the red bricks produced in Haidian Island.
After having money, Shen Fu's identity was completely different. Not only did he wear robes, but he also hired a master to teach him how to read and prepare himself.
When Shen Fu heard Xu Liu's report that a smallpox patient had appeared in the factory and the boiler workshop was about to stop production, Shen Fu became furious and cursed: "Stop production? Xu Liu, don't you want to stop working? Isn't it just a smallpox patient?"
Well, give him half a month off and let him go home to rest. If he survives it, he will come back to work!"
His temper increased after he was promoted. The current Shen Fu was not just a submissive person when he came here. Xu Liu secretly cursed this guy for being a villain, but he said: "Director, this is what the eldest wife of the Zhao family ordered!"
When Shen Fu heard that it was the eldest lady of the Zhao family, he immediately lost his temper. After a long time, he cursed: "Damn it, didn't you tell me earlier that the eldest lady of the Zhao family was here?"
Shen Fu quickly changed his clothes, ran all the way to Sun Jing, knelt on the ground and saluted: "Shen Fu didn't know that the lady was here, he is really guilty!"
When Sun Jing saw Shen Fu, he remembered that this was the brick-burning apprentice. Unexpectedly, Shen Fu had completely changed after not seeing him for a few months. Now he looked like an apprentice, wearing a robe and a melon-skin cap. He was said to be a
Even the wealthy country people did not disobey the rules.
The industry was under the control of his father-in-law Zhao Zhikuan, and Sun Jing did not want to interfere, so Sun Jing did not care about why Shen Fu changed his appearance, but directly said: "Shen Fu, there is a smallpox patient in your factory. If you don't stop production and quarantine, it will spread."
All over the island!”
After hearing this, Shen Fu said in a stern tone: "Ms. Zhao family, you know that Shen Fu is just the shopkeeper, and the old lady still needs to make the final decision on stopping production!"
Shen Fu originally wanted to fend off Zhao Zhikuan for a while, but when he saw that Sun Jing's face was not very good, he quickly stepped down and said, "But the lady's business is still important. Shen Fu will ask the workers to stop production!"
After a period of busy work, all close contacts have been isolated, and all the patient's contact objects have been burned. Sun Jing also found three people who have self-recovered from smallpox in the factory. After self-healing from smallpox, an infectious disease like smallpox will gain lifelong immunity, so Sun Jing asked these three people to recover from smallpox.
People deliver meals to quarantined people and take care of confirmed patients.
Sun Jing breathed a sigh of relief as she watched those close contacts go in for isolation obediently, but she knew that the matter was far from over. According to Sun Jing's estimation, there would soon be a large number of smallpox patients in the steam workshop. If no arrangements were made in advance, it was very likely that
The mortality rate will increase significantly.
It is completely unrealistic to rely solely on the patient's own immunity to hope that they will recover on their own. You must know that the mortality rate of smallpox is 30%. Sun Jing knows that these workers are Zhao Zhikuan's darlings, and they are also the capital of his husband Zhao Fuxiang's business, so he must not let them
Too many of these workers have died, so not only do they need to be isolated, but they also need to be treated.
Smallpox virus does not directly cause many deaths. Most of them are caused by organ failure caused by complications, such as meningitis, osteomyelitis and other infectious diseases. Therefore, the most effective way to deal with complications is to increase the patient's nutritional supply, and
Provide antibiotics.
Providing nutritional supplies is easy, just give them sugar water, but antibiotics are troublesome. The penicillin developed by Sun Jing is still not up to standard, with a mortality rate of about 10%. I really don’t dare to risk using it on these smallpox patients.
He did not die from complications, but from penicillin.
Since antibiotics cannot be used, prevention methods must be used, that is, smallpox vaccination.
Smallpox has been spreading in China for thousands of years, and Chinese medicine discovered it very early
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Nowadays, anyone who has had smallpox and recovered will never get smallpox again in his life. Although the ancients did not know the immunological principle of this, its practical value is reflected. The Chinese ancestors who are good at summarizing have such an idea
: Let smallpox patients with mild illness infect normal people. After the illness recovers, it will not cause death, but also can make people have the ability to avoid smallpox for life. This idea was put into practice, and a method to prevent smallpox was invented -
—Vaccination against smallpox.
There are four specific operations: the pox dressing method, the pox pulp method, the dry seedling method, and the water seedling method. The pox dressing method is to let normal children wear the clothes of smallpox patients; while the pox paste method, dry seedling method, and water seedling method all use
The acne pulp or scab removed from a mild smallpox patient was brought into contact with the nasal cavity of a normal child.
Although variola vaccination has greatly reduced the mortality rate, variola is still very toxic, so the mortality rate can only be reduced to about one percent. This mortality rate was still acceptable in ancient times, but in Sun Jing's case it was 10,000
Absolutely unacceptable.
Fortunately, there was a safer vaccination method in later generations, which was cowpox vaccination. In the mid-18th century, a British country doctor named Edward Jenner accidentally discovered that cowpox could prevent smallpox from a milkmaid.
After more than 20 years of research and experimentation, the cowpox vaccination method was finally invented.
The biggest advantage of the cowpox vaccination method is that the safety is greatly improved, because after people are infected with cowpox, in addition to causing mild lymphadenitis, there will be no acne, let alone fatal, and the mortality rate can be reduced to one in a million. Sun Jing
, Zhao Fuxiang and other people born in the 1970s all have a soybean-sized scar on their arm, which is the scar left after vaccination with cowpox.
Sun Jing remembered that the book at that time taught about cowpox that milkers contracted after encountering pustules on the breasts of cows. Could he try it himself?
Sun Jing remembered it correctly, but the correct cowpox is the weakened cowpox virus extracted from the infected fluid of calves. Only in this way can the mortality rate be reduced to one in a million. Although Sun Jing's method can also obtain immunity, it will cause death.
The rate is slightly higher than the correct vaccination method for cowpox.
In order to ensure the island's labor force, twenty or thirty cows were raised on the island. Sun Jing easily obtained this infectious fluid from some cows, but when it came time to inoculate it, those under her were not willing to do it first.
An inoculation. Everyone knows that smallpox can kill people. Who knows if you can make this thing effective? You don't want to die early if you live well.
Sun Jing herself has smallpox antibodies, so her vaccination with cowpox is of no use. At this time, her goddaughter Zhao Jing stepped forward and expressed her willingness to be the guinea pig. Sisters Xu Jinhua and Xu Jinhua also stepped forward together with Zhao Jing. They were grateful to Sun Jing.
The kindness of taking me in, so I am willing to believe in the eldest lady of the Zhao family!
Sun Jing was very pleased to see this. She decided to set an example for Zhao Jing. However, when it was time to get vaccinated, Zhao Jing couldn't stop vomiting. Seeing her like this, Sun Jing thought it was because her physical condition had declined due to fatigue in the past few days, so naturally she could not be vaccinated.
Regarding cowpox, you must know that vaccination with cowpox is not easy. You will also get a weakened form of smallpox, so those who are sick must not be vaccinated.
Sun Jing arranged for Zhao Jing to rest, and then vaccinated Sister Xu Jinhua with cowpox. The next step was to wait for the results. The process went smoothly. Sister Xu Jinhua developed symptoms of smallpox three days later. She had a fever and a rash on her body, but the severity was worse than that of the smallpox patients.
Much lighter.
Ten days later, both Xu Jinhua and the sisters recovered. The high fever had subsided. Except for a scar the size of a copper coin on her arm, there were no sequelae of smallpox on her body or face. Sun Jing knew that her experiment was successful.
(End of chapter)
Chapter completed!