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413, Pig heart transplantation

Su Jie stayed up all night last night. In addition, after eating Du Annan's breakfast, a large amount of blood gathered in his stomach, resulting in insufficient blood supply to the brain. He was already so sleepy that he could not open his eyes.

But after listening to what James said, he suddenly became energetic and his sleepiness disappeared.

"Pig heart transplant?"

Su Jie asked doubtfully: "Is that what you mean on the surface, using pig hearts to transplant patients?"

After saying this, Su Jie immediately felt a little confused.

Putting a pig's heart into a human chest...how is this possible?!

"That's right!"

James smiled. He obviously felt that Su Jie was already curious about this, and a doctor's curiosity often drives him to do many things, such as going overseas to complete a difficult transplant operation...

Seeing that Su Jie's appetite had been aroused, James thought for a moment and then explained:

"In fact, the most difficult part of a heart transplant is not the surgery, but the search for a heart donor."

"When we went to Shushan before, we talked in the car. For heart transplantation, heart donors are not only scarce, but must be living brain-dead patients before they can be donated. At the same time, there are strict requirements on the transportation process and time."

"This all means that it is very, very difficult to find a suitable heart."

"Many times, the surgeon is actually confident that he can complete the heart transplant, but the actual situation is that he has to wait for a long time and fails to find a suitable heart. The patient eventually reaches the end of his life unwillingly."

"Pig heart transplantation is one of the solutions we have found so far."

While listening to James' explanation, Su Jie drank the last mouthful of porridge and wiped his mouth with a tissue. He said, "Use pig hearts to replace human hearts. How do you want to solve the serious rejection reaction?"

You know, all transplant surgeries need to face a difficult problem... immune rejection.

The human immune system is a double-edged sword. It is not so smart that it can judge what is good for the host and what is bad for the host.

For it, the working principle is simple: remove all foreign organisms from the host's body.

And when it cannot be eliminated, the immune system's solution is even more mindless and cruel...perish together, cut off the life of the host, and cut off the energy supply to the alien organisms.

Therefore, kidney transplantation often prefers kidney transplantation from relatives. This is also a unique advantage of kidney transplantation, which can minimize the damage to the host caused by immune rejection.

But for other organ transplants, we can only try to find donors with a high degree of matching to minimize the possibility of immune rejection.

James gave the answer: "Gene editing."

"We deleted the genetic code that allows the pig heart to continue growing so that it can maintain the same size as an adult male heart."

"At the same time, in order to prevent rejection, we directly deleted the genes in the pig heart that may cause rejection, and added four human genes to improve the affinity between the pig heart and the host."

"Only Mayo in the world has the ability to transform a pig's heart into the shape of a human heart. The fake heart is enough to fool the human immune system."

"sharp."

Su Jie couldn't help but praise: "If pig heart transplantation can really succeed, it will undoubtedly be great news for transplant patients around the world who are waiting for heart donors."

James nodded heavily: "That's right! So Dr. Su, I sincerely invite you to go to the Mayo Center with me to complete this operation that may be one of the most glorious in the history of medicine!"

The idiom is really well used. James seems to have prepared a lot for today... Su Jie secretly smiled inwardly, seeing through James' long-premeditated rhetoric.

"I still have to discuss this matter with the leader. I can't give you an answer for the time being. And now..."

Su Jie pointed to his head: "My brain is so confused that I can't give you a clear answer."

James did not show any disappointed expression. He smiled and said, "Dr. Su, you have been busy all night. Now take a good rest."

"There is no need to rush the pig heart transplantation for the time being. The operation will take some time, enough for you to think about it seriously."

After saying that, he stood up and walked towards the door, and just when he was holding the door handle and preparing to close the door, James suddenly paused and said softly:

"Dr. Su, I believe you will not give up such a precious opportunity. I can see your enthusiasm for challenges."

The door was closed, but James' voice seemed to remain in the room.

"It's a challenge... I'm actually not very interested in challenges. It's a pity that this guy in the system and I are not on the same page."

Fatigue came over him like a tide, and Su Jie felt that he had completely lost the ability to think, so he threw himself directly onto the soft bed and fell asleep in a second.

Su Jie, who was sleeping, had no idea that after a night of fermentation, the Batu poisonous mushroom incident shocked the entire city the next day.

Many people wake up after a long sleep, only to find that their neighbors, relatives, and elders have all entered the hospital, and some have even entered the intensive care unit. They don't know when they will be released.

This is not a natural disaster, this is entirely a man-made disaster.

There should be accountability and responsibility, but after people are angry and dissatisfied, they should always have an opportunity to calm down their emotions, and the Badu News report appropriately provides this opportunity.

Reporter Cui and the cameraman had been filming at Southeast Hospital all night last night. Everyone had relaxed early in the morning, but they rushed back to the TV station and hurriedly edited out this morning's news report.

The news was broadcast, the narrow and dim observation room of Southeast Hospital was seen by more people, coupled with Dr. Jiang Wu's serious and steady explanation, and the reporter's summary of Southeast Hospital's perfect battle situation last night, all of this made the viewers feel excited.

A sense of security.

"Is it this young doctor who saved so many seriously ill patients last night?"

"Thanks to him, otherwise I might not even be able to see my father-in-law for the last time!"

"We in Badu are really lucky to have such an excellent doctor!"



Southeast Hospital, Office of the Director of Emergency Department.

Director Li Jianguo, who rushed back to the hospital from overseas last night, was sitting on the sofa. In front of him was a cup of espresso coffee and a tablet playing Badu news.

With a smile of relief on his tired face, Director Li Jianguo picked up the hot coffee, smelled the aroma, and then took a big sip.

At this moment, the cell phone rang. Director Li Jianguo glanced at the caller ID, then quickly sat up straight and answered the call.

"Yeah, yeah."

"Don't worry, Dr. Su Jie has always been a key training target in our department, and we have always attached great importance to him."

"He himself also likes the atmosphere of our emergency department. I have chatted with him in private many times, and he has no intention of leaving."

"Even before, he did not accept the invitation from the Mayo Center for exchange studies... Yes, the Mayo Center in the United States, the world's top medical center, has a huge temptation for every doctor."

"But Su Jie didn't go."

"So you can rest assured that Su Jie will definitely not leave Southeast Hospital or Badu. He will become the most reliable guardian of our city!"
Chapter completed!
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