Chapter 459: Artemisia annua, Artemisia annua, Artemisia annua
On a summer night, Yuwen Wen, wearing a short shirt and "cropped pants", sat upright in the side hall. With the light of the gas lamp, he flipped the book with one hand and sang a palm fan with the other. A plate of spiral mosquito coils was lit next to him, and there was a slight "whimpering" sound around him.
It was a hovering mosquito approaching Yu Wenwen who was reading a book, but was fumed by the smoke of the mosquito coil and fell to the ground one after another. After struggling for a while, there was no movement.
Yuwen Wen looked at the mosquitoes that fell to the ground and looked at the spiral-shaped mosquito coil. He was very satisfied: the strange chrysanthemum brought back from the extreme west was indeed a wormwood chrysanthemum.
The mosquito coil made of pyrethrum has obvious mosquito-killing and repellent effects, so it is now a cash crop that the imperial court vigorously promotes and grows. Wang Shichong has also received a generous reward from the emperor. In addition, he performed well in his tenure as the governor and was about to be appointed.
Now, Yu Wen Wen personally conducted an experiment, lit mosquito coils in the semi-open side hall without "air conditioning" to see how many bags of mosquitoes would bite him, but as of now, no mosquito has succeeded.
Effective mosquito repellent and mosquito killing methods are one of the prerequisites for large-scale development of the smoky and smoky land in Lingnan. However, mosquito coils alone are not enough, because people cannot carry lit mosquito coils with them all day, so there is still a possibility of being bitten by mosquitoes.
Once bitten by a mosquito carrying malaria, the bitten person will easily get malaria. If there is no special medicine for treatment, it is highly likely to die from malaria, and pyrethrum cannot cure malaria.
Therefore, if you want to effectively treat malaria, you either rely on artemisinin or cinchona cream.
Yuwen turned his gaze to the information in his hand and continued to read.
The "Shennong Hundred Grass Classic" between the Book of Books and Han dynasties records the medicinal effects of the plant "Artemisia delta":
It tastes bitter and cold, and is responsible for scabies, scabs, itchy scabs, and itchy scabs, kill insects, and keeps heat in the bones and joints; it is bright, and one is Artemisia annua and the other is ulcerated, which produces Sichuan and Ze.
Another paragraph of content is listed in the information: "Shuowen Jiezi" written in the Western Han Dynasty, which interprets "artemisia" as "artemisia, worm, worm, and worm".
From this we can see that during the Han Dynasty, doctors believed that Artemisia annua is Artemisia annua, which has a fragrant taste.
In the Eastern Jin Dynasty, Ge Hong wrote "Emergency Prescriptions for Elbows" that said Artemisia annua juice can treat malaria, but this statement is not a one-man statement. Many doctors know that Artemisia annua can treat malaria.
But the effect is just that. The patient's chance of recovering from Artemisia juice is not as high as expected.
Therefore, Yu Wenwen, who knew about artemisinin, invested a lot of manpower and material resources to develop methods to effectively extract artemisinin in order to subdue the beast malaria.
However, there has been no progress, and now he realizes that he may have made a mistake: the target plant for artemisinin extraction is not necessarily Artemisinin, or the Artemisinin-based Artemisinin is different from the Artemisinin he identified.
There is a difference between Artemisia annua and Artemisia annua, just like the difference between textile hemp and Indian hemp.
If you want to extract artemisinin that can cure malaria (get cannabis that can make people ecstatic), you have to choose the right target plant (select Indian cannabis). Otherwise, no matter how hard you try, you will never be able to extract artemisinin (using textile hemp to extract cannabis).
So, what kind of artemisinin is extracted from?
During this period, Yuwen Wen asked someone to sort out all the medical books and related classics that can be found in the world, sorted out the relevant information about the plant "artemisia annua", and re-examined the clues. The conclusion given by the information is that there are two main types of artemisia annua used to be used as medicine in the world, the first is Artemisia annua (artemisia sinensis).
Another one is called "Artemisia sacred".
Artemisia annua and Artemisia scented, but in terms of smell, Artemisia annua has a fragrant smell and Artemisia annua has a stinky taste (varied from person to person). Yuwen Wen knew this before.
But he recognized "Artemisia annua" and asked technicians to find ways to extract artemisinin from "Artemisia annua" that can treat malaria.
But there was no expected breakthrough.
Before, Yuwen Wen felt that the technology should be bad, so he couldn't do it after spending more than 20 years.
Now, Yuwen Wen feels that it is not because he has pointed the wrong direction, so the harder the technicians work, the further they are from the goal.
He actually only knew the term artemisinin. Of course he didn't understand how to extract it. It was just because artemisinin had the word artemisinin, so he naturally thought of extracting it from artemisinin.
Thinking of this, Yuwen Wen rubbed his temples. Many medical books in "ancient" describe medicinal plants in text. Even if there are schematic diagrams, the drawings are not very accurate. In addition, the words are concise, so it is easy to cause misunderstandings.
Once a certain medicinal plant depicted in the book has several extremely similar "fakes" in reality, it is difficult for people to tell which one is the "authentic" written in the book.
So, is artemisinin not extracted from "Artemisia annua", but from Artemisia atractylodes?
Yuwen put down the information, closed his eyes and sat steadily.
If this is true, then the various extraction methods that technicians have tried will have to be tried one by one due to the changes in the target plants, and it will take a lot of time.
Maybe another twenty years will be gone.
If Artemisia celadon is not the target plant for artemisinin extraction, it means that these "do it again" will still be useless.
After all, should we wait for the expedition to find cinchona from America and bring it back, or should we continue to invest a lot of money to let technicians conduct extraction experiments on Artemisia anise?
Yuwen Wen opened his eyes and put away the information.
Only fools do multiple-choice questions. Shouldn’t the normal answer be “I want them all”?
When walking on two legs, the success rate will always be higher. It is nothing more than to study how to extract artemisinin, but it costs much less than to develop a steam machine, and it is not impossible to afford it. It is nothing more than to take time.
If you are lucky, you may have gained something on both sides, if you are not lucky...
The expedition team "seeks seeds" in the Americas. Even if they can't find the cinchona tree, it's good to find peppers, tobacco and corn. If the technical team still cannot extract artemisinin, then accept their fate. What else can they do?
Yu Wen Wen, who was well-thought about his thoughts, noticed that the mosquito coil was about to burn out, so he asked the eunuch to come in and clean up, and walked out of the hall himself.
Looking at the stars in the sky, he began to think a lot again.
It has been more than two months since Zhangyu's fleet set out to now, and I don't know whether the fleet has successfully arrived in the New World.
Which civilization already existed in America in this era?
Aztec Mayan Inca or other civilization?
Yuwen Wen thought and walked, and his thoughts became more and more active. He thought of the Indian tribes in North America, the mountain cities in Central America, the pyramids in the rainforests in South America, and...
The Zhou Kingdom expedition team met the huge "screw boat" (spaceship) that was promoted from the sky. The humanoid creatures that came down from above were the gods in the minds of American civilization - the alien iron-blooded warrior.
After a bloody battle with the "Iron Blood" who is both righteous and evil, members of the Zhou Kingdom's expedition team had to join forces to deal with the brutal evil beast "Alien" in the tropical rain forest...
Chapter completed!