The effective recommendation period for the Nobel Prize is from September to January 31 of the following year.

The qualified referee is a former Nobel Prize winner, a university professor specially designated by the Nobel Prize Committee or the Nobel Prize Committee.

Most of the winners of Nuowu who are still alive recommend Shen Qi to select Nuowu again.

The Nobel Prize Committee also voted for Shen Qi, but Academician Stinga voted anyway.

In the history of the Nobel Prize, some people have rejected the Literature Prize, but no one has ever refused to receive the Nobel Prize in science.

As the winner of the two-time Nouwu, Shen Qi hopes to leave the opportunity to others. His attitude is: "Let it go."

Academician Stinga came to persuade Shen Qi to receive the award, and on the other hand, he did come to do academic exchanges.

"I am very sorry that I did not participate in the great experiment of black hole information paradox last year, but I read the paper published by Professor Chen on this experiment in full. The last lhc experiment proved that information will not disappear after entering a black hole. But I have a doubt, where did the information processed by wave function enter the black hole, and what specific form does it exist?"

"Karl, do you really want to know?" Shen Qi smiled, with a mysterious feeling in the calm.

"There is a Chinese proverb that you will die in the evening when you hear the truth. Yes, I want to know."

"You are good at Chinese literature, come with me."

Shen Qi immediately displayed an unpublished document.

Academician Stinga was stunned after reading it.

"Oh, it's a pity that this is just a deduction model... If it is true, how good it would be..." Academician Stinga murmured to himself. He really felt that Shen Qi was going to receive the Nobel Prize to give face to the Nobel Prize.

Afterwards, Shen Qi arranged for Sha Dongdong to take Academician Stinga to eat hot pot.

Next, Shen Qi received Academician Alexander Nelson.

Academician Nelson is a medicinal chemist. He and his assistants are very interested in the lpjk1 project of Shenqi Research Center.

The lpjk1 project is conducting animal experiments. The number of alternative active compounds is decreasing and there are still 5 active compounds left. Major pharmaceutical companies, including Glk, have inquired about the relevant situation of Shenqi Research Center.

Not only pharmaceutical companies, but some academic institutions are also paying attention to the latest trends in Shen Qi's laboratory. For example, Academician Nelson from the Royal Swedish Academy of Sciences is a group of scholars.

"Professor Chen, can we visit your medicinal chemistry experiment?" asked Academician Nelson.

"Of course." Shen Qi led his Swedish friends into the laboratory.

The central chemistry laboratory is currently on a semi-off state. Most researchers have returned home for the New Year, and only one doctoral student, Cao Fan, stays at his post to clean.

The active compounds of the lpjk1 project were sent to Tongzhou Animal Experiment Base for animal experiments. Twenty-two active compounds were continuously eliminated in the animal experiments, and there are still 5 left.

The laboratories are no longer as nervous and busy as before, and they show peace and peace.

If Academician Nelson and his group of people proposed to visit the laboratory two months ago, Shen Qi would not agree.

Now, just visit it casually.

Academician Nelson looked left and right and said, "Professor Chen, we saw the reports on the twenty-two macrocyclic compounds synthesized in your laboratory on the patent report. We were very excited, so we flew to China immediately to have in-depth communication with you."

When applying for a compound patent, a general synthesis route is usually attached, but patent applicants often do not give a complete synthesis route when applying for a patent.

Twenty-two compounds of the lpjk1 project of Shenqi Research Center have been patented. Like most patent inventors, they have not given a complete synthesis route.

The lpjk1 project innovated some important chemical methods in the process of preparing active compounds.

The 17 compounds that were eliminated had certain side effects on the animals, but these 17 compounds and the remaining 5 were stable in terms of chemical structure and chemical properties.

The twenty-two compounds are eight-membered heterocyclic compounds and macrocyclic compounds

Generally speaking, macrocyclic compounds are unstable. They can exist in chemical reactions, but it is difficult to obtain stable final products. Because of the instability of macrocyclic compounds, organic reactions about macrocyclic compounds are rarely developed.

This is also the main purpose of Academician Nelson and his group this time: "We all know that the five-membered ring and the six-membered ring are the most stable, and most chemical synthetic drugs are also the structure of the five-membered ring and the six-membered ring. When it comes to the HV drug direnavir, medicinal chemists will naturally associate the paterno-buchi reaction, or the aldol reaction that plays a key role in another synthetic pathway."

"Hmm." Shen Qi nodded, deeply agreeing with this.

Academician Nelson continued: "In the process of developing the prostate drug Suletan, Pfizer designed many synthetic routes to support the core reactions of each synthetic route. In the end, Pfizer chose a synthetic route with wittig reaction as the core because the raw materials for this route are the cheapest. The synthesis of five- and six-ring drugs has formed a very complete chemical synthesis system and developed a variety of human name reactions. The synthesis route of eight-component ring drugs involves almost no core reactions."

Shen Qi: "Yes, that's it."

Compared with Shen Qi's calmness, Academician Nielsen became more and more excited as he spoke: "Your chemical drug research and development team seems to have given a new idea. You have obtained twenty-two stable eight-membered heterocyclic active compounds with the newly developed rearrangement reaction as the core! I really want to know whether the synthesis of stable eight-membered heterocyclic compounds with the new rearrangement reaction as the core has universal rules? Or, can you share the complete synthesis route of the twenty-two macrocyclic compounds and the entire theoretical system that supports this synthesis route?"

"Professor Shen, your synthesis route in patent reports is too simple, right? Since you have applied for a patent, can we give a sneak peek and see more complete research results? Or, can you publish the latest research results of macrocyclic compounds as soon as possible in professional academic journals? Oh, Professor Shen, in my opinion, your research results can be compared with the 'discovered and developed diene synthesis method' and 'developed olefin metathesis method in organic synthesis'."

Academician Nelson made a generous speech, while Shen Qi smiled and refused to say anything.

The bystander Cao Fan was surging in his heart. Damn it? He discovered and developed the diene synthesis method and developed the olefin metathesis method in organic synthesis... These research results are all at the Nobel Prize in Chemistry!

But I didn’t make a fuss about it. It was a routine operation for Director Chen to make a Nobel Prize-level achievement.
Chapter completed!