Chapter 627 Active Compounds
After a day and night of fierce battle, cheers rang out in the laboratory: "It's done!"
New compounds were born, and then there were various tests.
Chemical structure test data show that this is an eight-membered heterocyclic compound.
"Director Chen, give this eight-membered heterocyclic compound a name." Cao Fan, who was growing up, said excitedly and expectantly.
Naming new compounds is a basic operation. Anyone in this laboratory can skillfully use more than three internationally common naming rules.
Some time ago, He Lin and Cao Fan made seven-membered heterocyclic compounds.
They use compounds a, b,...z to note these seven-membered heterocyclic compounds. If the English letters are used up, they will continue to use the combination of English letters + Arabic numerals.
In this project, compounds below eight yuan do not deserve formal chemical names because they are all process products.
Of course, these process products are also meaningful. Without a process, how can the results come about?
The newly released eight-membered heterocyclic compound is different. It needs to be tested for activity. If the activity test passes, the next step is to synthesize the drug.
The patent medicine has come out and passed several phases of clinical practice, and the project will be successful.
If the lpjk1 project is successful, it will not only be a victory in drug synthesis, but also a victory in basic theoretical research.
The comprehensive victory of academic research combined with engineering application is to save a life and build a seven-level pagoda.
At such a meaningful moment, the public unanimously suggested that Shen Qi operate the first eight-membered heterocyclic compound.
"Then I'm more respectful than obedience." Shen Qi clasped his hands together and expressed his gratitude. He thanked everyone for their efforts.
There are several principles for naming heterocyclic compounds in the world, and Shen Qi decided to use the Hanqi-Weidmann heterocyclic system nomenclature.
In this naming system, an unsaturated ring with the largest non-cumulative double bond number is generally used as the suffix. The three to ten rings correspond to the heavenly stems Jia, Yi, Bing, Ding, Wu, Ji, Geng, Xin, Ren, Gui, and those with more than ten yuan are eleven, twelve...
Based on the Hanqi-Weidmann heterocyclic ring system nomenclature, Shen Qi quickly gave the name: "1,3,4-triazaxin ring, thank you for your hard work, let's do the activity test."
The daily routine of chemical dogs is one experiment after another, one test after another.
Patriotism, dedication, integrity and kindness.
Since you have chosen this profession, you can live forever.
Activity testing is to select specific cells to process them as test cell lines, and then perform specific activity testing on the synthetic compounds.
The activity test result is OK, then this active compound can enter the animal experiment stage.
If it is not OK, then the previous saying "Saving a life is better than building a seven-level pagoda" is equivalent to blowing water.
The activity test of compound 1,3,4-triazacin ring is underway.
The experimenters cheered up and did the test.
"Okay! Activity test OK!"
Good news, the lpjk1 project finally has an active compound.
But an active compound is far from enough. What if it fails to pass animal experiments?
So you need to store more active compounds.
For a drug project, small pharmaceutical companies outside usually prepare two or three active compounds, while large pharmaceutical companies generally reserve more than 20. Pharmaceutical giants like Glk often prepare sixty or seventy active compounds.
The active compounds that have passed animal experiments have value in the market. If they pass the first phase of clinical practice, their value will continue to increase.
Most small pharmaceutical companies do not make new drugs. After obtaining active compounds, they sell them to large pharmaceutical companies after passing animal experiments or clinical first phase.
The second phase of clinical practice, the third phase is too expensive and small pharmaceutical companies can’t afford it.
The patent development rights of lpjk1 have been sold to Oubic Pharmaceutical, which is a factory cooperation laboratory.
Whatever Shen Qi's laboratory gives Oubeiqi Pharmaceutical, Oubeiqi Pharmaceutical will do.
"Continue to make active compounds and make derivatives of 1,3,4-triazacin ring." Shen Qi led everyone to continue to work hard, accumulate grain, and make more active compounds.
on Monday.
The Chemistry Laboratory of Shenqi Research Center made another good news: "It was successful and it was successful. The derivative 1 of 1,3,4-triazacin ring was synthesized!"
"It's OK! The activity test results of derivative 1 of 1,3,4-Triazaxin ring are very OK!"
Tuesday.
The Chemistry Laboratory of Shen Qi Research Center was excited: "It's done, and the derivative 2 of 1,3,4-triazacin ring has been synthesized!"
"No problem, no problem! The activity test results of 1,3,4-Triazacin ring derivative 2 are no problem!"
Wednesday.
"Damn, it's a failure!"
Thursday.
"It's amazing! The third derivative activity test is excellent!"
Friday is the same as Thursday, omitted.
Working overtime on Saturday, the result was similar to Wednesday, and it failed.
I continued to work overtime on Sunday, but the result was as great as Friday, so I can't forget to show it.
Including the 1,3,4-triazacin ring, in one week, the Chemistry Laboratory of Shenqi Research Center produced 6 active compounds that passed the activity test.
In other words, Shen Qi and his group make one active compound a day on average.
This efficiency is so terrifying.
The horror continues.
Led by a countless award-winning, leading mathematician and physicist, the Chemistry Laboratory of Shenqi Research Center produced 22 active compounds in one month.
Compared with the laboratories of large pharmaceutical companies, Shen Qi's laboratory has several times the efficiency and success rate that they are.
The lpjk1 project has been promoted to the current stage and the confidentiality level is very high.
During this sensitive period, Miss Lucy Walker of Glk Company visited Shen Qi on the grounds of academic exchanges.
Shen Qi met Lucy because of the last British academic delegation's visit to China.
The British academic delegation has long returned to Britain, and Miss Lucy stayed in China. Her current identity is the business leader of Glk China Corporation.
To put it simply, the last British academic delegation's visit to China was very successful. China and the UK reached a high degree of consensus on many academic research projects and engineering application projects, and will carry out specific cooperation in different fields in the future.
Shen Qi received the British delegation with his very friendly and professional professional qualities, which received high praise and deep recognition from the British side. The British expressed his sincere gratitude to the Chinese Foreign Office and sincerely hoped that the Chinese academic delegation would visit the UK soon.
In view of Shen Qi's outstanding performance in the field of diplomacy, the country has planned to arrange for Shen Qi to continue to host the French academic delegation, the Swedish academic delegation and the japan academic delegation.
Shen Qi received Miss Lucy who came to visit at the center cafe. He looked at the watch and said, "Lucy, I only have ten minutes to talk about it."
Lucy made a helpless and dissatisfied expression and said to himself that Professor Chen, you have changed.
Chapter completed!