Yanda Stadium, the school-wide sports meeting kicked off.

Shen Qi was wearing sportswear and running shoes and participated in the men's 100-meter preliminaries for the student group.

Bang! The gunshots, the game begins.

Eight contestants started.

Shen Qi, who was in the second lane, had a fair future and a strong future. He won the first place in the group with a time of 10.99 seconds and advanced to the rematch.

The 100-meter rematch of the student group was held in the evening, and many spectators came to the scene, most of them were students, as well as faculty and staff from Yan University.

There are 16 players in the two groups in the rematch. The competition system adopted is that the top two in each group will directly advance to the finals. The remaining players will compare their results, and the four with the best results will be qualified for the finals.

The first two places in the first group of the rematch were 10 seconds 75 and 10 seconds 81. The fifth place in this group reached 10 seconds 93, which means that there are five college students in this group that meet the first-level sprinter standards.

All five contestants are recruiting sports special students, the youngest one to be in the freshman year and the oldest one to be in the senior year.

First-level athletes are the basic requirements for entering Yanda Track and Field Team.

Yanda Track and Field Team has several athletes and an international athlete.

The fastest male athlete in this Yanda Track and Field Team is an athlete. He comes from the law school and is in his junior year and is in the second group of the rematch.

Shen Qi is also in the second group, and the athletes from the law school are on the runway next to Shen Qi.

The athlete was surprised that the famous Professor Shen actually entered the rematch.

"This athlete classmate, I heard that you are the fastest running man in Yanda. What is the PB?" Shen Qi said to the athlete next to him.

Athletic athlete: "10 seconds 43."

Shen Qi asked: "That's amazing. Can you join the national team?"

The athlete shook his head: "Professor Shen, the times have changed, and the national 100-meter record has reached the level of 9.90 seconds. Now that we have to join the national team, we have to run within 10.25 seconds."

"Everyone is in place!" the commander shouted a command.

The athletes stopped talking and made their starting postures.

Bang!

At the beginning of the competition, Shen Qi set off quickly. He ran over 50 meters and found that he had fallen to sixth place.

"These college students are really strong!" Shen Qi didn't know if he didn't run away. He was startled when he ran away. The second group was the Death Group.

In the last twenty meters, Shen Qi spared his life to increase his stride, surpassing the two, and won the fourth place in the group with a time of 10.79 seconds. After comparing the results with the first group, Shen Qi advanced to the 100-meter final.

This competition adopts the electrometer mode, and an anemometer is installed on the field. The final list of the men's 100-meter team in the student group is displayed on the large screen.

Shen Qi ranked fifth among all the players in the promotion. He ran a 10.5m/s record with a 10.79 second.

A professor was ranked fifth in the student group and ran within 10 seconds 80, which surprised many viewers.

Shen Qi looked at the big screen, and he was quite excited: "10 seconds 79, pb!"

Shen Qi's mentality is to enjoy the competition, and he ran the fastest one-hundred-meter run in his life.

Only by running through it can you deeply understand why the 10-second mark was considered the limit of yellow people, and it is really difficult to run into 10 seconds.

The other student contestants gathered around Shen Qi and were all surprised: "Professor Shen, your sprinting level is really professional!"

"Come on, young men. I, an old man in the thirty years old, will not show mercy in the final." Shen Qi laughed and left.

Today, two shots and 100-meter runs were so exciting. Shen Qi found the coach of the track and field team and said he wanted to get a first-level athlete certificate.

The coach said it was fine, 10 seconds 79 had exceeded the first-level athletes' standard line. At this Yandaquan School Sports Games, experts from the China Athletics Association were invited to assist. The competition specifications met the application requirements for first-level athletes.

The 100-meter final is scheduled to be held the next evening.

On the morning of the 100-meter final, Shen Qi participated in the men's long jump preliminaries for the student group. He jumped over the 7-meter passing line in his first jump and advanced to the long jump final.

After the jump, Shen Qi returned to the center to handle the related work.

When participating in sports competitions and competing with young people, Shen Qi felt that he had become younger and full of passion.

Passion is rippling, and inspiration is endless.

"By the way, I thought of it." Shen Qi had imagined the new target compound that he had not come up with for a long time, and had a new idea at this moment.

"With benzothiazine as the parent nucleus, the hydrophobic side chain of the n-dodecanoyl group is introduced, yes, it is it."

Shen Qi drew the conceived target molecule on paper and then began to reverse the problem.

The properties of organic compounds are mainly determined by the functional groups in the molecule. If the functional groups are attached to the molecular skeleton, the skeleton cannot be established, and the functional groups have no destination.

The synthesis of complex molecules includes changes from small to large changes in the molecular skeleton. The large skeleton of the target molecule is obtained from the small skeleton in the previous reaction step by step.

Shen Qi began to dismantle the target molecules, which required professional skills, derivation skills, and familiarity with various organic reactions.

Whether the selection of the molecular disassembly site is appropriate will play a decisive role in the success or failure of synthesis.

Shen Qi carefully disassembled a hydrazide compound. As for the temperature of this hydrazide compound under acidic or alkaline conditions, and what catalyst to synthesize the target product, there is no need to consider now.

During the route design stage, there is no need to consider too many limitations of reaction conditions, otherwise chemists will never design a synthetic route.

As for why the target molecule of the parent nucleus + hydrophobic side chain of benzothiazine is designed, one is that Shen Qi thinks this molecular structure is more interesting, and the other is that he has studied related literature before.

This target product could theoretically become a glycogenase kinase-3β inhibitor.

Glycosynthetase kinase-3β is a multifunctional serine/threonine protein kinase found in mammals. It is involved in regulating various physiological processes in the body and affecting a series of cellular functions through phosphating, including metabolism, differentiation, value-added, and apoptosis.

It has been reported in Europe that glycogen synthase kinase-3β inhibitors can be used to treat Alzheimer's disease, and a certain compound has been used in European clinical trials Phase Iib.

It has been reported in the United States that glycogen synthase kinase-3β inhibitors can be used to treat diabetes.

japan reported that glycomonas synthase kinase-3β inhibitors can be used to treat immune diseases.

Glycosyl synthase kinase-3β is widely distributed in the human body. This kinase tube is very wide. It can be seen everywhere in the central nervous system, metabolic system, immune system, and it is a target related to many diseases.

This is also the reason why Shen Qi chose benzothiazine as the parent nucleus + hydrophobic side chain as the target molecule.

"Put it backwards..."

Shen Qi pushed until the afternoon to see the time and had to go to the sports field to warm up.

Shen Qi had no psychological burden in the one-shot 100-meter final at night, enjoying the passion and the competition.
Chapter completed!