What Academician Zhong saw could no longer be described in words. A problem that the whole world could not solve was suddenly solved on the first day of the Chinese New Year?

at this moment,

Academician Chu, who was on the other end of the phone, heard the rapid breathing of his colleague Lao Zhong. He was confused for a moment and asked curiously: "Old Zhong... what on earth did you see? Why do you feel like your breathing is beginning to become rapid?"

Already?"

"I..."

"I can't believe... what I saw." Academician Zhong said sincerely: "Solved! Finally solved... I simply compared the two data reports, and the final results were almost identical..."

The words stopped abruptly here.

What Academician Zhong wanted to say suddenly got stuck in his throat, and his expression gradually changed from shocked to a little horrified, as if he had seen something that subverted his view of knowledge.

"wrong!"

"No, no, no, no!" Academician Zhong kept repeating a word with a horrified face. The hand controlling the mouse kept sliding the scroll wheel. His eyes became a little frightened at this moment. He discovered some content that could not exist at all.

"What's wrong?"

"What's going on?" Academician Chu was going crazy at this time. He wished that wings would appear on his back, and then he would fly to Academician Zhong to see what he saw. This mystery was so mysterious that it whetted people's appetites.

"Professor Xu Mang...he...he replaced the original Cas9 with another RNA-guided nuclease in the new CRISPR-Cas gene editing system." Academician Zhong said in surprise: "This is simply incredible.

..It’s so…amazing!”

Academician Chu:???

The more you can't see something, the more you want to have it.

Academician Chu is going crazy. Hearing the constant exclamations of his colleagues, his curiosity is being eaten away bit by bit, and he is about to collapse at the last bit.

"God!"

"He not only upgraded the CRISPR-Cas gene editing system, Professor Xu Mang also solved a...a problem that troubles all biologists around the world!" Academician Zhong said hurriedly: "He redesigned the c2c1 nucleic acid

Enzyme, now...c2c1 nuclease has been completely adapted to most organisms!"

Suddenly,

Academician Chu has completely collapsed. If the successful upgrade of the CRISPR-Cas gene editing system is just the beginning, then the redesign of the C2C1 nuclease is the straw that breaks the camel's back.

C2C1 nuclease has thermophilic properties, which makes it impossible to develop into a gene editing tool. Moreover, the key is that the original structure of C2C1 nuclease will cut non-target single strands in double-stranded DNA. The lower the temperature, the more errors will occur, leading to

Editing efficiency is low.

This problem is a problem all over the world. Many teams have tried hard but failed... However, Professor Xu Mang actually succeeded in breaking this dilemma?

this...

Is this killing two birds with one stone?

"Old clock!"

"Hurry up and send me the data!" Academician Chu urged impatiently: "I'm so itchy because of you... Hurry up, hurry up... Send me the so-called redesigned c2c1 nuclease. What exactly is it?

What's going on?"

"Ahem!"

"This article only introduces the effects of redesigning c2c1 nuclease, but does not give a detailed report." Academician Zhong frowned and said seriously: "Wait a moment... I need to give Professor Xu Mang a

Call me and ask what’s going on.”

The words fell,

Academician Zhong hung up the call directly and hurriedly called Xu Mang.

"Hello?"

"Professor Xu... you have redesigned the c2c1 nuclease. Is this true?" Academician Zhong asked nervously: "Are there any relevant research reports? And this needs to be verified experimentally. It can only rely on AI simulation.

It’s not convincing enough.”

Xu Mang said calmly: "There are relevant research reports. Although they have not been experimentally verified, from the research reports on c2c1 nuclease around the world, using AI technology... the results have been completely obtained. It is not impossible for c2c1 nuclease

For gene editing, it is very suitable."

"To put it simply..."

"The CRISPR-C2C1 gene editing system I developed has higher sensitivity, can achieve sensitive DNA detection, and can also achieve single-base distinction." Xu Mang said with a smile: "With my gene editing system, we can quickly achieve

Bacterial and viral infections, genotyping, and SNP mutation detection in cells, blood, and animals and plants."

"I'll ask Xiao Zhang and Xiao Cai to help me get the experimental data in a moment." Xu Mang said with a smile, "By the way...can Academician Zhong apply for a patent?"

"..."

"Can!"

"You have to give it to us for free." Academician Zhong said hurriedly: "By the way... call me as soon as you get the results."

"Um!"

"I want to publish it in Nature, right?" Xu Mang asked.

Academician Zhong said hurriedly: "Absolutely!"

hang up the phone,

Academician Zhong sent all six pieces of information to his old friend's email address. However, only half an hour later, he received a call from Lao Chu.

"this..."

"This is almost unbelievable!" Lao Chu said with surprise: "The only thing missing is a research report on the redesigned c2c1 nuclease. If Xu Mang can publish it, it will be even more perfect!"

"This is only the early stage... A brand-new gene editing system like this needs to continue to accumulate experimental data and constantly improve on the original basis, but... being able to come up with such a framework concept is enough to prove Xu Mang's greatness.

Academician Zhong smiled bitterly and said: "Old Chu... I have to lament that the waves behind the Yangtze River push the waves ahead, and each wave is stronger than the last."

at the same time,

Xiao Zhang and Xiao Cai were helpless. They were captured by Xu Mang again, but this time they had no complaints. They came into contact with Xu Mang's latest research results, about the redesigned c2c1 nuclease.

at this time,

The two are conducting relevant experiments for this new CRISPR-C2C1 gene editing system, and at the same time handling the C2C1 nuclease in more detail.

And this process,

It took two whole days. For Xu Mang, he didn't feel much in these two days. He just sat in the laboratory, cracking melon seeds and sending WeChat messages with Xiaoman. But for Xiaozhang and Xiaocai,

I gained a lot from these two days.

As a new intern researcher at the institute, it is rare to have access to such top-level research projects. However, Professor Xu Mang can not care about his own experience and let himself join this research and become a part of this research. This kind of kindness is simply indescribable.

in return.

"Are you ready?"

"This speed is not bad..." Xu Mang said with a smile: "You can go and rest...or you can go outside, I am here in the institute."

Not to mention,

At this time, the two of them were exhausted. After saying hello to Xu Mang, they hurried back to their dormitory.

Xu Mang checked the relevant research reports, silently went to his office, turned on the computer and started editing the paper, and wrote the name of the paper at the beginning - "crispr-c2c1 gene editing system".

...

London,

The headquarters of the famous scientific magazine "nature",

Originally, this day was an ordinary day for the editors of "Nature", but some people didn't want this group of people to live too easily. At this time, a paper that was about to shock the world was quietly arriving at Pitt.

Editor's email.

"Nature's top ten figures of the year will be published in the order of this list." Editor-in-chief Pete said to one of his subordinates: "Be sure to pay attention to the order."

In the list submitted by Editor-in-Chief Pete, Xu Mang was ranked first. There was no way... Although the entire Western world did not want to see Xu Mang ranked first, his achievements this year were no longer able to be

Use shady control.

"Editor-in-Chief Pete..."

"A lot of people will be very unhappy if the Chinese are ranked first." The young editor said, "How about... moving it back?"

"no!"

"You can't move at all." Editor-in-Chief Pete said seriously: "Look at the achievements of the next nine people. Their combined achievements are only half of Xu Mang's. Do you think there is any theory to prevent Xu Mang from taking the first place?"

for a time,

The young editor was speechless. This was really the situation.

moment,

Editor-in-chief Pete is the only one left in the office. I don't know what has happened recently. The quality of the papers is very poor, and the man he is looking forward to has never appeared. It may be because China is at this stage of what they call the New Year.

Well?

New email alert?
To be continued...