Act XIV Only a lunatic patented penicillin
"Okay, my Consul Tanni, don't worry about how penicillin is produced. Anyway, you only care about money." Roger was too lazy to explain his plan to Tanni, nor could he explain it, because he didn't trust the foreign devil at all, and his current cooperative relationship was more about using each other.
"Remember two key points: First, don't apply for a patent! Second, the name of this drug is called antibiotic x in the future. The name of the penicillin I mentioned before should be absolutely confidential. It is best to forget it directly! I don't want anyone to associate the source of the drug through the name of the drug!"
"I can understand the name change, but what a joke!? Don't apply for a patent!? Are you crazy?" Tanny thought he was crazy about Roger's request. If his magic medicine is not applied for, what if their magic medicine is copied!? Then wouldn't all his investment be wasted!?
Roger shook his head and explained, "If I apply for a patent, it's really crazy. Do you know what it means to apply for a patent? It means we have to disclose all the secrets of penicillin! And twenty years later, the patent will be gone! No protection will not exist! Patents are only twenty years after all, but what if we can keep the secret for a longer time? For example, thirty years?"
"If that's the case, it's better not to apply for a patent, but...if...if..."
"Nothing in case, I can guarantee that even if our factory is full of commercial spies, no one can produce penicillin without me!"
This is completely guaranteed, because the factory does not produce penicillin at all, and it cannot produce it even if you want to...
"Well, since you are so sure, then do what you said, but if you find that others have shown signs of developing penicillin, then we will apply for a patent right away!"
“There is no problem with this!”
In fact, there is another very important reason why Roger refused to apply for a patent - the significance of industrial production of penicillin is not just a magical life-saving drug produced. It has created a new model for discovering antibiotics - looking for new drugs from microbial metabolites!
After the success of penicillin, researchers took this as an example to screen drugs from various microbial samples. New drugs emerged like mushrooms after a rain, and squeezed out a large market for penicillin in a short period of time!
If you apply for a patent for penicillin, the source of penicillin will inevitably be announced! Other drug manufacturers will inevitably understand that there is also a trick to screen antibiotics from microorganisms. As long as they have this trick, they can easily find new drugs to replace penicillin!
In this way, Roger will definitely not be able to do a monopoly business. When only penicillin is a life-saving drug, it can sell a sky-high price of three gold bars, but when there are too many oleracillin, streptomycin, erythromycin, and xxmycin that make you dizzy, penicillin can only be a bargain price!
It can be said that from the moment when the penicillin patent application was successful, the huge profits of penicillin did not exist! Even if you can only make money for ten years, you might be able to make such a thing happen! So, until the last moment, Roger would not consider any patents!
Facts have proved that Roger changed the drug name, did not apply for a patent, and purchased chemical synthesis equipment achieved good results. Until the moment when Roger took the initiative to apply for patents for more than 100 antibiotics, including penicillin, no one could discover the secret of penicillin!
Everyone thinks penicillin is a synthetic product, but it is a metabolite of microorganisms; everyone thinks penicillin is produced by chemical synthesis, but it is produced by fermentation; even everyone in Roger's factory thinks they are producing penicillin, but they are producing auxiliary materials for penicillin...
...
Although he reluctantly agreed to Roger's two requests, Tanny's heart hangs, and a thought suddenly flashed in his mind, and he asked hurriedly: "Are you sure there is no problem with the production process of this drug?? Although your major is pharmacy, laboratory and factory are completely different concepts!"
"Of course there is no problem! I'm asking for specialized talents to help, so there's absolutely no problem, so don't worry!" Roger patted his chest and promised that he had not been idle for the past half month. It only took four days to treat Mrs. Tanny. The rest of the time, Roger returned to modern times. He spent a few hundred yuan to buy a complete set of technical information for penicillin production. He also found a pharmaceutical factory to examine the details of the production process, get the specifications and lists of equipment needed, and bought a high-yield penicillin strain for industrial production to make some preparations for the real penicillin production factory in the Republic of China in the future. Fortunately, penicillin, an outdated and not very profitable thing, has only spent 10,000 yuan to purchase the strain.
What's more, the factory he currently builds does not produce penicillin at all!
For antibiotics that require microbial fermentation, even if there is the most advanced production process, it will be useless without high-yield strains. The reason why penicillin was difficult to mass produce was not just a problem with the production process, but also an important reason for the absence of high-yield strains. The penicillin strains used in modern times are super varieties mutagenic after decades of cultivation. Under the same conditions, the yield is much higher than the original strains isolated naturally.
On March 1, 1943, the Pfizer penicillin factory was completed and put into production. The new factory with 14 huge 7,500 gallon fermenters can produce 45 million units per month, which is more than 5 times the original expected output. In modern times, a large-dose penicillin injection is 1.6 million units, and tens of millions of units are often hung with water. It is a month-long production for treating headaches and fevers. For penicillin, the most fundamental factor in the increase in output is the improvement of strains. Without good strains, even if you are the king of heaven, you can't make a lot of money on penicillin.
Although I was still a little worried, now that things have come to this point, Tanni had no other way except to go all the way.
Tanni sighed and said, "I will do the mechanical matter immediately. If there is a shortage of funds, I will find a way. It should be no problem to borrow from the family. But in addition to the matter of the pharmaceutical factory, I hope to talk to you about another thing."
Seeing Tanni's expression becoming frowning, Roger smiled and said, "What? Is the compensation matter a big deal?"
;
Chapter completed!