Chapter 148 Hypothermia circulatory arrest selective cerebral perfusion surgery
"Sorry, I shouldn't have moved other people's things. Sorry, I just..." Sophia realized that this was someone else's room, and behavior without permission was impolite, so she quickly put down the notes in her hand.
Shi Yinuo didn't think anything was there and asked Sophia, "Are you a doctor too?"
"I'm not a doctor. I just like to read medical books because I've also suffered from terminal illness since I was a child. I forgot which book I saw. Why, did you say something wrong?"
"No..." Shi Yinuo sighed without much ease, "You are right. This is all the problems I face. Only by solving these problems can I save my friend's life, but they..."
Sophia came over and held Shi Yinuo's face and comforted, "Don't be discouraged. Every progress in the history of medicine is accidental and continuous hard work. Most terminal illnesses a hundred years ago have treatments today. I believe that as long as you work hard, everyone can create history. Come on, I believe you can do it."
The pressure and smile appeared on Shi Yinuo's face at the same time. Sophia was right, but creating history was not as simple as she said.
"By the way..." Sofia suddenly asked, "Have you heard of the "Human Hypothermia Surgery Plan"?"
Shi Yinuo smiled. Isn’t this a graduation thesis written by himself? It was just that it was originally called “Deep Low-Cycle Stop Selective Brain Perfusion Surgery Plan”, but after it was translated, it became a simple and easy-to-understand but very inaccurate name “Human Hypothermia Surgery Plan”.
Although this paper caused a great sensation in the European medical community when it was published, it still surprised Shi Yinuo, an ordinary person who read this paper. It seems that she really likes reading medical books.
"I know that biological metabolism is largely determined by temperature. The cryogenic surgery plan refers to rapidly reducing the body temperature to between 16-18 degrees, causing the patient's breathing and heart to stop, the metabolic rate is almost zero, and it is in a temporary state of false death, protecting important organs from damage caused by hypoxia and ischemia during the operation, thereby minimizing the trauma and risk caused by the surgery, that is, the purpose and meaning of the word "deep low temperature".
Two requirements must be met for this kind of operation. The first is that the blood in the whole body must be drawn out of the body, otherwise it will cause the risk of blood clots in the body, that is, the meaning of "stop circulation". The second is that it only ensures normal blood supply to the brain to prevent permanent brain function damage, that is, the meaning of "selective brain perfusion".
After getting Shi Yinuo's detailed explanation, Sophia suddenly realized the problem that she had not understood before, and nodded thoughtfully and said, "So that's it, the person who invented this surgical plan is really a genius. The human body reduces its metabolism to 0 under low temperature and fake death, and in large-scale operations, it can avoid damage caused by fragile organs due to ischemia and hypoxia."
Shi Yinuo smiled and said, "You are right. I admit that the kid is a genius. Unfortunately, he cannot continue with something, which leads to this surgical plan being theoretical and there are no clinical implementation cases."
Sofia heard Shi Yinuo say this and asked curiously, "Do you know him?"
"I don't know..." Shi Yinuo shrugged.
"But since you know this, don't you think this is a surgical plan for your friend's weak body mass? After reducing metabolism to zero, all problems will be solved. Although her body organs, including the heart, will not be further damaged during the operation. It is just right that the time of stopping can be used to repair the defect."
This is the purpose of Sophia suddenly mentioned this with Shi Yinuo. At first glance, it gives people the feeling that Lin Yun was saved. He couldn't find any problem, but Shi Yinuo shook his head.
"Do you know what else you need to want someone to have a near-stop metabolism, besides low temperatures?"
"What?"
“Hydrogen sulfide.”
“Hydrogen sulfide!?”
Most people may not know what this is, but Sophia clearly understands it. The so-called hydrogen sulfide is a chemical substance. Under standard conditions, it is a flammable acid gas, colorless and highly toxic. When it is high in concentration, it can paralyze the nerves of people's olfactory system. In the gas state, it is white smoke-like. Normal people only need to inhale O.2 mg and fall into a paralysis state. It also has a strong metabolic inhibitory effect. One gram can permanently stop metabolism.
To put it bluntly, it is a poison.
"Hydrogen sulfide is used to assist in stopping metabolism in cryogenic surgery, but the dosage must be very accurate. I won't tell you what the consequences are if it is less or more?"
Sofia frowned tightly, "The patient will die, but... but how could he think of using hydrogen sulfide to help stop metabolism... this crazy way?"
Shi Yinuo said embarrassedly, "Because no matter whether it is simply reducing the human body temperature to the lowest safe range or using hydrogen sulfide, it is not enough to make the metabolism meet the surgical conditions. And..." Shi Yinuo thought for a while and continued, "That madman didn't deliberately want to use poison. Perhaps because he didn't find a suitable replacement, the instructor was like urging death, and he could only write hydrogen sulfide on it. After all, it was just a theoretical surgical plan, and it was nothing to write it casually."
Sofia asked again, "In other words, if this problem is not solved, the hypothermia surgery solution can only exist in theory?"
"That's right."
Yinuo had already considered the operation when using the cryogenic surgery plan to perform Lin Yun, but hydrogen sulfide could not find anything that could be replaced. Perhaps there is, should Lin Yun take the risk of being a guinea pig?
Obviously Shi Yinuo absolutely does not allow this to happen.
"What else can I do?"
Shi Yinuo smiled bitterly and was about to say something, but suddenly the expression on his face froze. He stared at Sophie's face and eyes were not blinking, just as if he suddenly found that he had left him hundreds of millions of pocket money.
"Doctor Shi, what are you looking at? Is there anything dirty on my face?" Sophia touched her face.
"I understand! I have found a way to replace hydrogen sulfide." After saying that, Yinuo walked over and picked up the notebook and quickly called a name on it.
"Grandpa?" Sophia frowned even more as she looked at the two Chinese characters, "Can your grandpa replace hydrogen sulfide?"
A big stone pressing on his heart hit the ground, which was a major breakthrough. Shi Yinuo felt unprecedentedly relaxed and wanted to pick up Sophia and kiss her hard. If this woman hadn't been suddenly visiting, she would have proposed the surgical plan for "Selective Brain Perfusion for Low Temperature Suspension and Circulation" that he gave up for a long time. He might have never thought of finding a way to replace hydrogen sulfide in his life.
"My grandpa can't replace hydrogen sulfide, but a friend he knows should be able to do it."
"Is the surgical procedure feasible?"
"Um."
After hearing this, Sophia rushed over and hugged Yinuo and cheered, "yes!yes!! I've said you can do it long ago."
At this moment, Qi Yuan pushed the door open and came in. Seeing Sofia and Shi Yinuo holding each other and not knowing what they were doing, they coughed twice and could only pretend that they didn't see anything.
"Ahem..."
Shi Yinuo let go of Sofia's direction to the park, "Why did you come?"
"I didn't I tell you last time that the hospital has been in chaos recently. Let's talk about me, even Vice President Tong is so busy that he has no time to drink water."
Shi Yinuo signaled Sofia, "I won't introduce what you know."
Qi Yuan looked at Sophia and his heart beat, "Is something wrong again?"
Shi Yinuo told Qi Yuan about Sophia's purpose, "It shouldn't be difficult for you to be busy. Say hello to the logistics side and borrow the drug storage room. The three coagulation factors do not occupy much space."
Qi Yuan hesitated and said, "No problem, no problem, but the three coagulation factors are enough to buy all the medicines in the entire drug storage room. If they lose them... who is responsible?"
Before Shi Yinuo could speak, Sofia explained, "Don't worry about this. If I lose it, I will say I accidentally lost it and ask my family to send it to me."
“…”
Qi Yuan looked at Shi Yinuo with a strange look, and thought to himself that he would look back at the royal family in Europe and his surname, and what is the origin of this person named Sophia.
"Then let the hospital go, it probably won't be thrown away. The drug storage room can't be entered except for the internal staff of the hospital."
"Okay, thank you Dr. Qi and Dr. Shi. I'll get it in the car now."
Seeing Sophia leave, Qi Yuan stared at Shi Yinuo and asked, "What are you doing? Gu Hongyue is such a good girl. I advise you not to step on two boats, otherwise I will give you some color even if she can't kill you."
"Wow, Lao Qi, why do you speak sarcastically? I don't understand what you mean..."
"Don't think I didn't see it." Qi Yuan pointed at Shi Yinuo, "What did you two hug each other just now?"
Shi Yinuo explained with a shameless face, "Is it strange for foreigners to hug each other? Do you believe it if you are anxious or kiss me?"
A few minutes later, a silver-white insulated box was taken back, with only two ice packs inside for temperature control. Of course, the exact temperature control difference between the hospital's medicine storage room was more than one level. Qi Yuan was afraid that the drug would be ineffective if it was delayed for too long, so he immediately took Sophia to the storage room.
After they left, Yinuo returned to their desk and saw the name on their laptop. He took out his cell phone and found a number that he had not called for a long time. A short old man's face appeared in his mind. There was no expression on that face, which seemed unfathomable, but when he saw Shi Yinuo, he turned into a smile.
"I don't know how my grandpa is in the countryside." As soon as he muttered, he answered the phone. Shi Yinuo's face changed and shouted loudly in a hoarse and rough voice.
"Old man, your grandson is in our hands. I will immediately take 100 million to redeem people, otherwise I will tear the votes."
"What, Yinuo is in your hands?" The old man's voice came from the phone. He sounded pretty good. Obviously, he really didn't hear who called the phone.
"Oh, why does this kid always cause trouble for me? I'll discuss whether he can get a discount?"
"Thirty-five, it can't be less."
(End of this chapter)
Chapter completed!