"Show me your experimental records."

"How are you doing now?"

When Yang Rui came to the laboratory, he asked all the way. He rarely did this. In fact, few people in large laboratories would do this. On the one hand, they did not have time, and on the other hand, they lacked their abilities.

It is obvious that there is no time. The person in charge of any large laboratory is busy. They either spend time in the laboratory or spend time raising funds. If anyone wants a senior laboratory director to revolve around him all day, he would be the Flash or something else.

Inadequate ability is another kind of helplessness. Laboratory work is no longer known work. No matter how easy the work of scientific research dogs is, it is still on the edge of the unknown world. If the laboratory leader can explain all the problems, he will not need the scientific research dogs to work hard to do experiments. Therefore, the unknown problems encountered by scientific research dogs are also unknown problems for the laboratory leader. Perhaps the latter has more experience in solving these problems, but it also takes a lot of energy and time.

Therefore, the higher the laboratory, the less guidance the laboratory head will provide.

Give systematic training, point out the direction of development, provide cutting-edge information, and have high-level brothers, basically the person in charge of high-end laboratories, and the most valuable things that can be provided. Of course, if you consider more secularism, the experimental and social resources of high-end laboratories are richer, it is also a benefit.

However, Yang Rui is not an ordinary laboratory director.

Facing the unknown scientific world, the heads of other laboratories may be like scientific research dogs, waiting for the results of exploration in darkness. The best situation is just holding candles to search.

But for Yang Rui, the scientific world of the 1980s was brighter and clearer than the playground under the noon sun.

Therefore, he is indeed capable of providing step-by-step guidance.

However, in the past, Yang Rui would not do this, mainly because he was not confident enough. In addition, he did not know enough about detailed, especially detailed things. It was only after several years of high-intensity laboratory life that Yang Rui had a high level of detailed domain control.

The most important point is that there was no need to guide scientific research on dogs in the past.

If a dog with 0 attacks and 0 defenses can already conquer the world, why do you still need to use a lot of resources to upgrade? Just like the enemy tanks are only 40 mm of armor for defense, we already have anti-tank weapons with 60 mm penetration. It is obviously not an urgent task to produce anti-tank weapons with 100 mm penetration.

Until now...

If we study PCR, the scientific defense system encountered is 40 mm armor, the defense system of G protein coupled receptor is about 400 mm armor.

The defense level of PCR is the defense level of Japanese small tanks, and the defense level of G protein-coupled receptors is a perfect maritime battleship.

The three-dimensional structure that Yang Rui is trying hard to achieve is almost equivalent to the core part of the battleship G protein coupling receptor. You can't buy the 400mm reinforced armor and suffer losses...

Faced with such a powerful enemy, it is impossible not to upgrade the scientific research dogs.

Especially when encountering scientific research dogs like Wu Qi, since they want to develop talents and provide resources, Yang Rui decided to start with the most powerful ones.

Yang Rui read the experimental record, and he pointed out the mistakes casually and raised the directions casually.

"Control your reaction temperature."

"You need to consider more about the use of solvents. Why should the concentration be placed at the current value? Do you have to use these types? What is the basis for the choice?"

"A big mistake, do it again!"

Yang Rui spent a morning killing a pair of people in the laboratory.

It’s okay for the students in the laboratory, but several professors who have joined the laboratory were shocked by Yang Rui.

Since Your Excellency Li Bixi, the teaching model of high-end laboratories has not changed much in the past 100 years. At that time, Giesen Laboratory always compressed theoretical teaching to a minimum, and most of the time guided students to do experiments and trained them in a three-step manner. The practice of handing over beginners' teaching to skilled students is exactly the same as postgraduate education in later generations.

Now, Yang Rui has done the opposite.

When he arrived beside Wu Qi, Yang Rui stood still and stopped leaving.

"There is no problem with the operation. How do you look at the results of this experiment?" He looked at Wu Qi after completing a set of experiments and asked.

Wu Qi straightened his waist, breathed a sigh of relief, and felt so stressed that he couldn't breathe. He quickly turned his mind and said, "If you analyze it from this substrate experiment..."

"Don't analyze it from an experiment. What do you think after you have done so many days of experiments?" Yang Rui interrupted Wu Qi in an instant.

Wu Qi was stunned for a moment and couldn't help but hesitate. There was no need to say the difficulty of analyzing an experiment and a bunch of experiments. Moreover, he was not prepared to let him say it out at once.

Yang Rui waited quietly for a few minutes. He had higher expectations for Wu Qi, so he also made extremely high requirements.

However, Wu Qi seemed to have not yet entered the state, and he looked like a statue with his avatar down.

Yang Rui didn't feel disappointed, but felt a little lost and surprised.

"That's it..."

"I think..."

While Yang Rui spoke, Wu Qi just looked up and spoke.

"You talk first."

"You talk first."

The two of them spoke in unison again.

Yang Rui couldn't help but smile, shook his head, raised his chin, and signaled: "Have you come up with the result?"

"Something is a bit of a thought..." Wu Qi didn't dare to say too much.

"you say."

"Yes." Wu Qi thought for a while before saying, "I have been doing experiments recently and I am more concerned about hydrogen bonding."

Hydrogen bonds are common intermolecular forces. In junior high and middle school, their value is basically equal to a "-", but in advanced research, hydrogen bonds are very diverse.

Yang Rui didn't expect Wu Qi to say it from this perspective, with a "Oh" sound, "Tell me, let me see."

"Yes." Wu Qi paused again and said: "I read some literature and believed that the directionality and saturation of hydrogen bonds are the driving force that causes the association between the receiver and the substrate, and then form the complex, and the important reasons for molecular recognition."

Yang Rui nodded slowly: "The focus of the G protein-coupled receptor we are doing now is molecular recognition."

"Yes. So I've been paying more attention to hydrogen bonds recently. I think that if the classification of substrates is taken into account with the factors of hydrogen bonding, some substrates should be able to be screened out. These substrates should have a higher chance and be used in conformational analysis." Wu Qi said very slowly, and even one sentence was broken up by him into several sentences.

However, what Wu Qi said is indeed worth thinking about, including Yang Rui, listened very seriously.

Moving towards the right goal may be "a road in Huashan since ancient times" or "all roads lead to Rome". When limiting funds, resources and scientific basis, the probability of the former appearing is greater than the latter. However, after the various restrictions are lifted, the possibility of the latter appearing increases.

Wu Qi proposed that it was a path that Yang Rui had never seen through - in fact, it could not be considered a failure. Scholars need to make the conformation of G-protein-coupled receptors. They chose some methods, which did not include hydrogen bonding paths. Later, the conformation of G-protein-coupled receptors was completed. Whether there are other methods or ways to reach the goal of conformation loses its practical significance.

As for now, Yang Rui feels that he can go ahead.

Anyway, he has so many scientific research dogs under his command, so it is also great to send a smarter person to explore the road.

Thinking of this, Yang Rui nodded slowly and said, "You write a report to me and explain your thoughts. Will you write such a report?"

"I can." Wu Qi nodded excitedly, submitting a report directly to the laboratory director is a step forward for scientific research dogs.

Yang Rui nodded and said, "I will give you a separate fund, 10,000 yuan. After the report is written, you will try the hydrogen bonding method alone. If it can be done, you will be allowed to sign and publish the paper separately. Of course, if it cannot be done, then go back to the regular route."

"I will do it." Wu Qi suppressed his mood, full of the heroic spirit of a scholar as a confidant.
Chapter completed!