Anyone who comes to lobby Yang Rui, Yang Rui is ready to go back head-on.

In the worst case, you can also turn on the mode of "I don't listen, I don't listen, I just don't listen".

However, Yang Rui couldn't even listen to Professor Cai's words.

He left Cao Baoming and Wang Guohua who followed him and let the two of them wander around the laboratory. Yang Rui invited Professor Cai into the office.

Professor Cai did not hide his purpose, and sat down. He first mentioned Jingxi Pharmaceutical Factory. Then, he talked about Jingxi Pharmaceutical Factory's investment in biological experiments over the years. Then, the topic changed and said: "Jingxi Pharmaceutical Factory cannot hold on anymore. They used to produce tablets and powders. Now factories in the south are open one by one, and the selling price is even lower than their cost. They have snatched their former customers. Qin Hanchi's agent for Sanmu's medicine is his last move. If it fails, thousands of workers at Jingxi Pharmaceutical Factory and the raw material factory that serves them as suppliers will all be in trouble."

"Do you know Qin Hanchi?" Yang Rui asked.

"I've seen it, but this time Lao Zhang asked someone to come to me." Professor Cai continued to explain: "Lao Zhang is from the GMP Preparatory Committee and has also supported you by-election before. In addition, several old friends from the Ministry of Health also called."

When Yang Rui followed Professor Cai to conduct projects and achievement appraisal, he had seen Professor Cai have a wide connection, but from the other hand, broad connections meant that he had to bear broad friendship costs.

Yang Rui nodded silently and continued to listen.

Seeing this, Professor Cai said, "If you have any ideas, just tell me. If you can tell me, I will tell them if you can. If you can't tell me, let's discuss it together."

Then, Professor Cai smiled and said, "Although I am here to help Qin Hanchi, I can also help you."

Yang Rui smiled bitterly: "Why do everyone think I have ulterior motives?"

"kindness?"

"I don't trust the drug Luboding, so I asked them to supplement safety tests." Yang Rui said helplessly: "The public research report of Luboding is not sufficient, and it is very risky to be rashly produced and promoted domestically."

"There is greater risk than Chinese patent medicine?"

Yang Rui was speechless. In this regard, he and Professor Cai are not on the same order of magnitude.

After thinking for a while, Yang Rui said: "The scale of use of Luboding is larger than that of Chinese patent medicines. In addition, Luboding is designed to take medicine for a long time. Therefore, if there is a safety issue, its risks will continue to accumulate. I think it is not a mistake to be more rigorous."

Professor Cai looked at Yang Rui for a while and suddenly said, "This doesn't look like your style."

"What is my style?" Yang Rui was stunned.

"Go ahead." Professor Cai gave his own answer.

Yang Rui recalled that when he was making potassium ion channels, he was indeed indomitable. PCR was relatively simple, but the subsequent lawsuits were worth millions, so he didn't want any reconciliation. He fought forward in an endless manner, and the subtext of "indomitable" was a huge risk.

Yang Rui was quite ashamed. Thinking about it this way, he did have some problems of "one time and another time".

"When you talk about me now, isn't your reputation very nice?" Yang Rui used his face too much, and he could guess how the people viewed him.

When "one time and another time" is linked to power, there will never be anything good.

Professor Cai nodded and said, "The scale of Jingxi Pharmaceutical Factory is also among the top in the country. Qin Hanchi has been the factory director for nearly ten years and is not a bad person."

Yang Rui sighed and said, "I don't want to be a bad person either."

"Then let Jingxi Pharmaceutical Factory pass the customs."

"There is something wrong with Lu Boding." Yang Rui stopped talking around and answered directly.

Professor Cai naturally asked a question that Yang Rui didn't want to answer further: "What's the question?"

Yang Rui could not answer.

As an anti-cardiorrhiza drug, the basis of its academic research is actually very stable. It is determined that premature beat is a disease, and then the premature beat is associated with more serious heart disease. Then, it is determined that inhibiting premature beat is beneficial to reducing the risk of heart disease. This entire academic chain is not done by day or two, nor is it done by one person or two. This is an academic research established by hundreds of scholars and more than ten years ago. Luboding is just a star product.

Anticardiac rhythm drugs were even more than one drug, but in the 1980s, almost all large pharmaceutical factories were involved.

And in the past decade, during the development of multiple drugs, has no one questioned the entire academic chain?

Of course there is.

However, academic discussions are only academic discussions after all. The most important problem is that anti-cardiac rhythm theory does not have fundamental flaws.

Even Yang Rui cannot say clearly that the anti-cardiogram theory is wrong.

The anti-cardiac rhythm theory may not be wrong. Using the simplest thinking, it is better to think that it is better to have premature heart attacks than to have premature heart attacks. After all, premature heart attacks are always an abnormal physiological phenomenon. If it can be treated or suppressed at no cost, it may seem like a good thing.

Therefore, the key to the problem returns to the safety of Luboding itself, or the drug itself.

So, how to prove the safety of Luboding?

Yang Rui knew that the problem of such anti-cardiogram drugs lies in their impact on electrical impulses.

But it’s nothing to say. Miki Company made a file cabinet to prove its safety and efficacy tests.

For Yang Rui, the best way to prove it is clinical trials, because the side effects of Luboding are hidden and take a long time to show. Therefore, ordinary clinical trials with a small scale and not long time are not enough. Hundreds or even thousands of patients with arrhythmia need to be found for double-blind tests. Half of them take Luboding and half of them take placebo, which is equivalent to a large-scale clinical phase one.

As for Yang Rui’s experience in doing ferrosterone, it would cost about 40 million US dollars, and it would be almost done in half a year. Of course, there must be some patients with possible heart damage, and there may be a few more people.

Can Yang Rui give out $40 million? Of course he can't get it. He hasn't seen much milestone payment for ferrosterone. Besides, he can't do this even if he can. He has $40 million and can research a new drug.

If you don’t conduct clinical trials and engage in academic debates, Yang Rui’s current status will not be able to compete with others.

There are also great people in the research group that worked on Lu Boding. They have been working on this medicine for nearly ten years and have memorized more information than Yang Rui has seen. Even if Yang Rui can speak eloquently, they cannot surpass the strength of passing the FDA.

To be honest, the criticisms received by the FDA have always been too low in efficiency and too high requirements, but there are few cases of unstricken reviews.

There may be some incomplete reviews in Luboding, but in terms of the concealment and slowness of its side effects, the FDA has actually done a good job.

The FDA may have asked all the questions that Yang Rui could ask verbally.

"The key now is not the problem of proving the Luboding problem, but the Jingxi Pharmaceutical Factory, which is to prove to me that there is no problem with the Luboding problem." Yang Rui's eyebrows drooped, then quickly raised them, and said, "Professor Cai, I'm sorry, I have to give you a face, I have to be responsible for my signature."

"Even if Jingxi Pharmaceutical Factory finds more people to put pressure on you, you won't let it go, right?" Professor Cai asked calmly.

Yang Rui nodded slightly.

"You have to know that Qin Hanchi not only found me, but in order to pass the Lu Boding, all the Jingxi Pharmaceutical Factory were thinking of solutions. And..." Professor Cai lowered his voice and said, "Their reasons are also abundant."

"I know."

"Aren't you afraid?"

"I'm afraid, I'm so scared." Yang Rui smiled bitterly. If he wasn't afraid, why would he call Wang Guohua and Cao Baoming over?

Even without violence, Yang Rui was not sure how long he could last. As the saying goes, he only knew Guan Xiao and the taxi drivers in Beijing were all around and could know a department-level cadre. Qin Hanchi himself was a department-level cadre, and what level of cadre could he contact?

Yang Rui did not live in a vacuum when he was a senior official.

However, Yang Rui asked himself, he might not be able to completely stop Lu Boding, but it would be better if he could delay it one day. If Lu Boding enters China one day later, the influence of the Chinese people may be fewer than thousands or tens of thousands, or some may survive because of this. Moreover, there will definitely be many people, thus eliminating the risk of heart damage, and thus living for several years or more years may be possible.

Furthermore, the delay in production of Jingxi Pharmaceutical Factory may also reduce the supply of Luboding in the global market. If the supply of pharmaceutical factories is reduced, the pharmaceutical representatives will not be so hard to promote it. The number of patients taking Luboding may also be reduced, and less deaths will be lost. In any case, Americans are also humans, and it is a bit too sad to die in a serious drug.

Professor Cai looked at Yang Rui's expression, but inexplicably realized Yang Rui's state of mind, just like the Yang Rui he saw in Tangjin Laboratory back then.

"This is still your style." Professor Cai sighed.

Yang Rui looked at him.

"Your style." Professor Cai pointed at him with his finger and said, "Go forward."
Chapter completed!